Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes
Enterocyte cholesterol homeostasis reflects aggregated rates of sterol synthesis, efflux, and uptake from plasma and gut lumen.Cholesterol synthesis and LDL uptake are coordinately regulated by sterol regulatory element-binding proteins (SREBP), whereas sterol efflux is regulated by liver Siemens LC87KHM60B iQ300 80cm Angled Cooker Hood - Black X r